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KMID : 0358420110540120836
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 12 p.836 ~ p.840
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A giant endometrial polyp with tamoxifen therapy in postmenopausal woman
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Moon Soo-Hyeon
Lee Seong-Eui
Jung In-Kook
Jeong Ju-Eun
Park Won-Young
Yi Woo-Hee
Suh Dong-Soo
Yoon Man-Soo
Kim Ki-Hyung
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Abstract
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Tamoxifen is a synthetic non-steroid anti-estrogen that has been used effectively for several years in the adjuvant treatment of breast cancer. But, the drug has been associated with development of endometrial poylp, hyperplasia and adenocarcinoma possibly mediated through its agonistic estrogen properties during the menopausal period in which estrogens are at a low level. Endometrial polyp has been described as the most common endometrial pathology in association with postmenopausal tamoxifen treatment. We present the case of woman with a giant endometrial polyp of uncommon dimension who was receiving adjuvant tamoxifen for 5 years after breast cancer surgery.
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KEYWORD
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Tamoxifen, Polyp, Breast neoplasm
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